<p><img src="https://www.lddbioscience.com/storage/blogs/uriplex-drops.jpg" alt="Uriplex-Drops"><br>&nbsp;<strong>Global cases of HYPERURICEMIA exceed 41 million with an 'alarming rate' of increased burden</strong></p><p>Hyperuricemia occurs due to high uric acid levels in the blood. Today’s sedentary lifestyle in Asian Countries has been the number one factor responsible for a high number of cases.&nbsp;<br>Hyperuricemia can also be caused because of increased alcohol consumption, high levels of meat ingestion or high levels of seafood ingestion.</p><p>There is a strong association that links Hyperuricemia directly to Cardiovascular diseases therefore increased uric acid levels should be constantly monitored and controlled in the general population with the help of URIPLEX DROPS.<br><br><strong>Indications</strong></p><p>• Uriplex Drops effectively relieve Symptoms associated with hyperuricemia (High level of uric acid) like severe pain/stiffness/ redness/ swelling in the joints etc.</p><p><strong>Ingredients</strong></p><p>• Berberis Vulgaris 3X<br>• Lycopodium Clavatum 3X<br>• Urtica Urens<br>• Taraxacum 3X</p><p><strong>Symptoms or causes</strong><br><br>• Uriplex drop is a safe, side-effect-free medicinal solution for hyperuricemia.&nbsp;<br>• Hyperuricemia can be defined as uric acid elevation level in blood due to urate overproduction and decreased uric acid excretion.&nbsp;<br>• Urate overproduction may occur because of purine-rich diet, error of purine metabolism, and certain disease conditions like hemolysis, rhabdomyolysis, tumor lysis, etc.&nbsp;<br>• Acute or chronic kidney disease can reduce uric acid excretion. [1]<br>• Gout is a very classic condition associated with hyperuricemia. [1]&nbsp;<br>• The acute gouty attack represents severely inflamed and very painful joint/s that peaks within hours.&nbsp;<br>• Inflammation is followed by hotness, redness, tenderness, swelling, and loss of function.<br>• Knees and ankles, skin signs are the joints usually get affected with intense pain and swelling. [2]</p><p><strong>Mechanism of action of Uriplex drops</strong></p><p>• Berberis vulgaris, Lycopodium clavatum, Urtica Urens, Taraxacum Officinale are four medicinal plant extracts that are blended to formulate Uriplex drop.&nbsp;<br>• Xanthine oxidase plays a vital role in uric acid formation. [3]<br>• The primary mechanism of action of Uriplex drop against hyperuricemia is inhibiting the xanthine oxidase (XO) enzyme.&nbsp;<br>• Berberis vulgaris extract can inhibit the xanthine oxidase enzyme and act as an anti-hyperuricemia effect.&nbsp;<br>• The pre-clinical trial result reported the efficacy of Berberis vulgaris against hyperuricemia or gout. [4]<br>• Uriplex drop containing Lycopodium clavatum can slow down protein metabolism and provide a remedial benefit against gout.&nbsp;<br>• Lycopodium clavatum ingredient is also improving uric acid excretion by preventing kidney stone production. [5]&nbsp;<br>• Lycopodium clavatum also acts as a xanthine oxidase inhibitor to treat gout. [6]<br>• Urtica Urens has potential anti-inflammatory effect and anti-arthritis effect. In Homoeopathy, Urtica Urens are widely used for the treatment of uric acid-related problems such as gout, uric acid diathesis, and joint pain. [7]&nbsp;<br>• Taraxacum Officinale can eliminate uric acid by increasing urine output. [8] Taraxacum Officinale also has kidney protective benefits. [9]</p><p><strong>Dosage</strong></p><p>• 10 drops in some water, 3 times a day 1 hour before or after meals or as prescribed by the physician.</p>